Eukaryotic translation initiation factor 4B is a protein that in humans is encoded by the EIF4B gene.

Interactions

eIF4B has been shown to interact with and stimulate the activity of eIF4A and bind to the eIF3 complex through the eIF3A subunit. This interaction results in the recruitment of the eukaryotic small ribosomal subunit (40S) to the mRNA which will in turn set the stage for the later steps leading to elongation.

See also

  • Eukaryotic translation
  • eIF4F

References

Further reading



Structural basis for the enhancement of eIF4A helicase activity by eIF4G

EIF4B (eukaryotic translation initiation factor 4B)

Volume 136, Issue 3, Pages (February 2009) ppt download

EIF4B Antibody 179171AP Proteintech

EIF4B Gene GeneCards IF4B Protein IF4B Antibody